Lub Plaub Hlis 1, 2020, FDA tau muab ib tsab ntawv tshaj tawm ntawm nws lub vev xaib thov kom tag nrho cov khoom lag luam tawm los ntawm lub khw vim tias qhov tsis lees txais ntawm impurities N-nitrosodimethylamine (N-nitrosodimethylamine) tau kuaj pom hauv qee cov tshuaj. , Xa mus rau raws li NDMA)
NDMA
NDMA tau muab cais ua qeb 2 Lub cev nqaij daim tawv. Nws yog cov tshuaj uas tuaj yeem tsim mob qog nqaij hlav hauv tib neeg. Nws yog sai sai los ntawm kev zom zaub mov thiab ua pa thiab maj mam nqus los ntawm daim tawv nqaij, feem ntau ua rau daim siab mob. Feem ntau tib neeg kuj tseem tuaj yeem noj cov zaub mov NDMA tsawg los ntawm kev noj haus, tab sis cov qis qis yuav tsis ua rau muaj kev pheej hmoo mob qog noj ntshav. Tab sis kev noj qab haus huv ntau ntau yuav ua rau muaj kev pheej hmoo mob cancer, xws li mob ntev ntev uas yuav tsum tau siv tshuaj ntev.
Kev tshawb nrhiav pom tias txawm nyob hauv ib qho chaw cia khoom zoo li cas, NDMA cov ntsiab lus ntawm ranitidine cov khoom lag luam yuav nce ntxiv. Thiab thaum qhov kub nce ntxiv, NDMA cov ntsiab lus yuav nce siab, thiab raws li lub sijhawm khaws cia nce, NDMA cov ntsiab lus tseem yuav nce.
Ranitidine
Ranitidine, tseem hu ua furanidamine, yog ib qho muaj txiaj ntsig histamine H 2 receptor antagonist, uas tuaj yeem tiv thaiv kev mob plab uas ua rau muaj kev cuam tshuam los ntawm kev sim tshuaj histamine, pentagastrin thiab carbachol, thiab txo qis plab acid acid lub plab ua si.
Ranitidine tuaj yeem siv hauv tsev kho mob los kho tus mob duodenal, mob plab, mob plab, mob es mob plab, thiab lwm yam kab mob uas ua rau muaj kev mob plab ntau dhau.
Ntawm tam sim no, tseem tsis muaj xaus hais tias cov khoom lag luam ranitidine muaj NDMA li impurities puas tsuaj rau tib neeg lub cev, thiab qhov kev ntsuas tseem yuav tsum tau ua.
Yog tias koj txhawj xeeb txog kev nyab xeeb ntawm ranitidine, koj tuaj yeem xav txog kev siv cov famotidine, cimetidine, omeprazole, omeprazole, lansoprazole thiab lwm yam tshuaj. Cov.
