CAS 209467-59-4 (2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-1-(1,3-benzothiazol-2-ylsulfanyl)-2-[(triphenylmethoxy)imino]ethan-1-ib

1. Tus qauv impurity reference tseem ceeb rau daptomycin synthesis Raws li -isomer ntawm daptomycin, nws yog ib tug yam ntxwv impurity nyob rau hauv zus tau tej cov txheej txheem ntawm daptomycin. Nws tuaj yeem ua tus qauv siv impurity hauv kev tswj xyuas kom pom cov ntsiab lus ntawm cov isomer no hauv cov khoom kawg, ua kom cov purity thiab kev nyab xeeb tshuaj ntawm daptomycin.

2. Cov qauv sib xyaw ua ke rau cov qauv- kev tshawb fawb kev sib raug zoo ntawm cov tshuaj tua kab mob Nws cov qauv zoo ib yam li daptomycin tab sis txawv ntawm kev teeb tsa. Nws tuaj yeem siv los kawm txog kev teeb tsa ntawm daptomycin li cas -zoo li cov tshuaj tua kab mob cuam tshuam rau lawv txoj haujlwm lom neeg, pab txhim kho cov qauv tshuaj molecular thiab txhim kho kev ua haujlwm ntawm cov kab mob.

3. Pab reagent rau kev kawm txog cov tshuaj tiv thaiv kab mob tshuaj tiv thaiv kab mob Nws tuaj yeem siv los ua cov cuab yeej sim, ua ke nrog daptomycin, txhawm rau tshawb xyuas seb cov kab mob tsis zoo rau cov tshuaj tua kab mob lipopeptide no puas muaj feem cuam tshuam rau cov qauv isomer, muab cov ntaub ntawv txhawb rau kev txhim kho cov tshuaj tiv thaiv tshiab - tshuaj - cov tshuaj tiv thaiv kab mob.