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Lub npe
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daprodustat
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Synonyms
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daprodustat, daprodustat;
2-(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carboxamido) acetic acid;
N-[(1,3-Dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]glycine;
DAPRODUSTAT; 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid;
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CAS Nr.
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960539-70-2
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MF
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C19H27N3O6
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MW
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393.43
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EINECS No.
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691-659-9
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Melting Point
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237 - 241 degree
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Qhov ntom
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1.359 ± 0.06 g / cm³ (Tshaj tawm)
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Kev cia khoom
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Lub tub yees
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Solubility
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Me ntsis soluble hauv chloroform, me ntsis soluble hauv DMSO
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Acid{0}}Base Coefficient (pKa)
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3.44 ± 0.10 (Kev kwv yees)
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Morphology
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Khoom
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Xim
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Dawb rau tawm - dawb
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Kev siv
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Siv rau kev kho mob ntshav qab zib nrog rau cov kab mob raum ntev (CKD), tshwj xeeb tshaj yog rau cov neeg mob uas tsis tuaj yeem txais lossis tsis kam lees rau cov tshuaj txhaj tshuaj erythropoiesis ib txwm muaj -cov tshuaj stimulating (xws li EPO). Raws li qhov ncauj HIF-PHI tshuaj, nws txo qis HIF- degradation los ntawm inhibiting HIF-PH, yog li ua rau kev tsim cov tshuaj endogenous erythropoietin (EPO) kom txo cov ntshav qab zib.
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Cim npe nrov: cas: 960539-70-2 daprodustat, Tuam Tshoj, manufacturers, lwm tus neeg, Hoobkas, kev cai, lag luam wholesale
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