| Khoom npe: | D-Serine |
| Synonyms: | (R)-2-AMINO-3-HYDROXYPROPIONIC ACID; β-Hydroxyalanine; D-SERINE 98.5%; D-Serine,>99% yog '; D-2-Amino-3-Hydroxypropionic; (2R)-2-amino-3-hydroxy-propanoic acid; D-Serin; (R)-2-amino-3-hydroxypropanoic acid |
| CAS: | 312-84-5 |
| MF: | C3H7NO3 |
| MW: | 105.09 |
| EINECS: | 206-229-4 |
D-Serine Chemical Properties
| Melting point | 220 degree |
| alpha | -14.75 º (c{2}} N HCl) |
| Boiling point | 197.09 degree (kev kwv yees ntxhib) |
| ceev | 1.3895 (zeeg) |
| Refractive Index | 1.4368 (kwv yees) |
| cia temp. | Khaws nyob rau hauv qhov chaw tsaus, inert cua, chav tsev kub |
| solubility | H2O: 0.1 g/mL, ntshiab, tsis muaj xim |
| pka ua | 2.16 ± 0.10 (Tswj) |
| daim ntawv | Crystalline hmoov |
| xim | Dawb |
| Dej Solubility | 346 g/L (20 ºC) |
| Merck | 14,8460 |
| BRN | 1721403 |
| InChIKey | MTCFGRXMJLQNBG-UWTATZPHSA-N |
| LogP | -1.490 (yog) |
D-Serine Siv thiab Synthesis
| Chemical Properties | D-serine yog ib qho dawb crystalline hmoov uas muaj ntxhiab tsw tsw ntxhiab.Nws yog ib qho amino acid pom nyob rau hauv lub hlwb. Muab los ntawm Glycine, d-serine yog ib qho neuromodulator, txhais tau tias nws tswj cov haujlwm ntawm cov neurons. |
| Siv |
Ib qho proteinogenic amino acids koom nrog hauv biosynthesis ntawm purines thiab pyrimidines. Inhibitor ntawm serine palmitoyltransferase. Ib tug neuromodulator. D-Serine koom nrog hauv biosynthesis ntawm purines, pyrimidines, thiab lwm yam amino acids. D-Serine kuj yog ib qho agonist ntawm glycine site ntawm NMDA-type glutamate receptor. Nws kuj ua raws li Lacosamide nruab nrab. D-serine tau siv los ua substrate hauv D-amino acid oxidase (DAO) kev ua haujlwm hauv tib neeg 1321N1 astrocytoma hlwb. Nws kuj tau siv rau hauv kev tswj hwm intracerebroventricular hauv nas rau induction ntawm antinociceptive nyhuv. |
| Txhais | D-serine yog R-enantiomer ntawm serine. Nws muaj lub luag haujlwm ua NMDA receptor agonist, tib neeg metabolite thiab Escherichia coli metabolite. Nws yog D-alpha-amino acid thiab serine. Nws yog lub hauv paus conjugate ntawm D-serinium. Nws yog conjugate acid ntawm D-serinate. Nws yog ib qho enantiomer ntawm L-serine. Nws yog ib tug tautomer ntawm ib tug D-serine zwitterion. |
Cim npe nrov: d-serine cas no.312-84-5, Suav teb, manufacturers, lwm tus neeg, Hoobkas, kev cai, wholesale
