CAS: 60142-96-3 Gabapentin Nr

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CAS: 60142-96-3 Gabapentin Nr
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Gabapentin (CAS: 60142-96-3) yog ib qho tseem ceeb hauv kev kho mob anticonvulsant thiab analgesic API, uas yog cov qauv analogue ntawm gamma-aminobutyric acid (GABA).
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Gabapentin API CAS 60142-96-3|Pharmaceutical Qib|GMP Certified Bulk Supply

Cov ntawv thov tseem ceeb

 

Anticonvulsant: Adjuvant kev kho mob rau ib nrab qaug dab peg (nrog lossis tsis muaj kev sib txuas ntxiv) hauv cov neeg laus thiab menyuam yaus hnub nyoog 3 xyoos; kuj rau kev kho mob ntxiv ntawm cov tshuaj tonic generalized-clonic qaug dab peg hauv cov menyuam yaus hnub nyoog qis dua 12 xyoos.

Analgesia: Thawj - kab kev kho mob rau cov neeg laus postherpetic neuralgia (PHN); adjuvant kho rau lwm yam mob neuropathic (xws li, mob ntshav qab zib peripheral neuropathy, trigeminal neuralgia).

Lwm Daim Ntawv Thov: Adjuvant kev kho mob rau kev ntxhov siab vim, nyob tsis tswm ceg syndrome (RLS) thiab cawv tshem tawm syndrome hauv kev kho mob, nrog kev nyab xeeb zoo thiab ua siab ntev

Mechanism of ActionPrecautions rau kev siv

 

Nws tsis khi rau GABA receptors los yog metabolized rau GABA lossis GABA agonists. Nws cov txheej txheem tseem ceeb yog xaiv los khi rau 2δ subunit ntawm voltage-gated calcium channels nyob rau hauv presynaptic membrane ntawm lub hauv nruab nrab paj hlwb, txo cov calcium influx thiab inhibiting tso tawm ntawm excitatory neurotransmitters (xws li, glutamate, norepinephrine), yog li txo cov neuronal hyperexcitability rau excitability thiab excitability. mob-txo cov teebmeem.

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