3-Methyl-1 - [(3s) -2-oxooxolan-3-{- {- {-{-thiazol-4-uran-2-}

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3-Methyl-1 - [(3s) -2-oxooxolan-3-{- {- {-{-thiazol-4-uran-2-}
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CAS: 1004316-93-1
Mf: c13h19n3o3s
MW: 297.37
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Khoom npe:
3-Methyl-1 - [(3s) -2-oxooxolan-3-{- (60-thiazol-4-thiazol-4-yl] methyl} urea
Cov lus txhais lus:

3-Methyl-1 - [(3s) -2-oxooxolan-3-YL] -3 - {-(arezol-4-thiazol-4-aum) methyl} urea;

(S) -1 - [(2-ISPropropyl-4-ISPropropyl-4-oozolyl) methyl] -1-oxo-oxo-3-tetrahydrofuranyl) urea;

Urea, n - Methyl -}}}}} {{12 {{{{{{{12} thiazolyl] methemicalbookthyl] -n '- [((3s) -Tetrahydro-2-oxo-3-furanyal] -;

(L) {- 1 {}}}}}}}} ayloryl-3- (2-oxotetrahydrofuran-3-yl) -ea;

(S) -1 - ((2-isopropyliazol-4-yl) methyl) -1-methyl-3 (2-oxoetrahydrofuran-3-yl) urea; rgica-358

CAS:
1004316-93-1
Mf:
C13H19N3O3S
Mw:
297.37
3-Methyl-1 - [(3s) -2-oxooxolan-3-{- (60-thiazol-4-thiazol-4-yl] methyl} urea
Puab kua
Xim Lub teeb xim av rau xim av

Kub taw tes

564.2 ± 50.0 Degree (kwv yees)
Ceev 1.27 ± 0.1 g / cm3 (kwv yees)
pa kua muag 12.30 ± 0.20 (kwv yees)
Flash point > 70 Degree
So Dmo kom yaj
Cia Temp
mob tsawg dua lossis sib npaug rau 25 degree, noo noo, zam kev tshav ntuj ncaj qha.

Kev siv

Kev siv

Kws Tshuaj Nruab Nrab

(1) cov ua haujlwm ua ntej rau cov tshuaj tua kab mob / tshuaj tiv thaiv kab mob

The thiazole ring is the core structure of many antibiotics (such as cephalosporins and fluoroquinolones) and antifungal drugs. Cov compound no yuav raug siv los ua ke:

Cov neeg ua haujlwm tshiab cov neeg sawv cev (xws li Oxazolidinone thiab TetrahyDrofuran {}} fused thiazole derivatives rau tshuaj {1} {resive bacteria).

Cov tshuaj tiv thaiv kab mob (xws li txhim kho cov qauv ntawm fluconazole thiab Echinocandin chav kawm).

(2) Central Ntshav Ntshav Nruab Nrab (CNS Tshuaj)

Tus qauv Tetranturan (Thf) feem ntau pom nyob rau hauv neurotransmitter modulators (xws li 5 - h receptor thiab Gaba receptor Ligands).

Cov compound no yuav raug siv los ua ke:

Kev ntxhov siab thiab cov tshuaj tiv thaiv kev tiv thaiv kev ntxhov siab (xws li thiazole derivatives ntawm 5 - ht repkurke inhibitors).

Cov tshuaj piv (xws li txhim kho cov qauv ntawm opioid lossis tsis - opioid analgesics).

(3) anticancer sawv cev

Kev sib xyaw ua ke ntawm Thiazole thiab cov pab pawg urea tuaj yeem tso cov compound nrog Kinase Inhibitt ua haujlwm (xws li EGFR thiab Vegf inhibitors).

Cov compound no tuaj yeem yog ib qho nruab nrab rau cov tshuaj anticancer, siv los ua ke TetrahyDrofuran {}} {1} {1 ur urea anta anta anta anta anta anta anta anta anta anta ante anticancer cov neeg sawv cev.

Agochemical intermediate

Lub nplhaib Thiazole yog cov qauv tseem ceeb ntawm ntau cov tshuaj tua kab thiab cov fungicides thiab fungicides (xws li thiazole fungicicide thiab pyrazole cov tshuaj tua kab).

Cov compound no yuav raug siv los ua ke:

Cov pwm tshiab (xws li thiazole fungicides muaj tetranahydrofuran).

Cov tshuaj tua kab (xws li thiazole -} urea compounds ua yeeb yam ntawm cov kab leeg hlab).

Cim npe nrov: 3-Methyl-1 - [(3s) -2-oxooxolan-3-{- {-{-}

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