Phage genome muaj cov nucleobase ntau yam tshuaj lom neeg uas muaj nyob thoob plaws hauv txhua lub neej. Qee cov kab mob DNA uas kis rau tus tswv tsev (xws li cyanobacteria, proteobacteria, thiab actinomycetes) muaj qhov tshwm sim uas amino adenine hloov pauv tag nrho adenine, yog li tsim peb hydrogen sib txuas nrog thymine, uas ua txhaum txoj cai Watson-Crick pairing. Amino adenine encoding DNA polymerase homologous rau cov kab mob DNA polymerase I Klenow ntu uas muaj 3-exonuclease tab sis tsis muaj 5-exonuclease kev ua haujlwm tau pom hauv deoxynucleoside triphosphates nrog thymine raws li tus qauv Thaum lub sijhawm koom nrog txheej txheem, amino adenine yog qhov tshwj xeeb siv tsis yog adenine.
Cov noob polymerase tshwm sim nyob rau tib lub sijhawm zoo li cov noob ntawm biosynthetic enzyme, uas tsim cov amino adenine deoxynucleotides hauv ntau yam kab mob bacteriophages ntawm tus kab mob Schizospora. Phylogenetic clustering ntawm polymerases thiab biosynthetic enzymes tau qhia tias aminoadenine thiab adenine tau nrog DNA rov ua dua txij li theem kev hloov pauv yav dhau los.
Cov ntaub ntawv ntsig txog:
Https://doi.org/10.1126/science.abe6542
Tau qhov twg los: ChemNet
| Adenine CAS NO.73-24-5 | |
 | adenine yog ib qho ntawm purine nitrogenous hauv paus uas sib xyaw DNA thiab RNA; tsim los ntawm ob lub pa roj carbon -nitrogen rings. Adenine sib txuas nrog thymine hauv DNA thiab nrog uracil hauv RNA (saib hauv paus txoj cai ua khub); nws kuj yog ib feem tseem ceeb ntawm lwm cov lwg me me xws li adenosine triphosphate. |