Cov ntaub ntawv yooj yim
|
Khoom npe |
Trelagliptin |
|
Synonyms |
SYR-472;2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,{{ 8}}dioxopyrimidin-1-yl]methyl]{10}}fluorobenzonitrile; UNII-Q836OWG55H; (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo{21 }}, 4-dihydropyrimidin-1(2H)-yl)methyl){26}}fluorobenzonitrile. |
|
CAS |
865759-25-7 |
|
MF |
C18H20FN5O2 |
|
MW |
357.38200 |
Chemical Properties
|
Melting Point |
Tsis muaj ntaub ntawv |
|
Cia Temp. |
Qhov kub yuav tsum tsis pub tshaj 37 ° C |
|
Cov tsos thiab cov khoom |
Dawb rau beige khoom |
|
Psa |
97.05000 |
|
Logp |
1.29888 |
|
Qhov ntom |
1.57 |
|
Boiling Point |
Tsis muaj ntaub ntawv |
|
Refractive Index |
Tsis muaj ntaub ntawv |
|
Flash Point |
Tsis muaj ntaub ntawv |
Siv thiab Synthesis
|
Siv |
Troglitin intermediates |
|
Kev piav qhia |
Tsis muaj ntaub ntawv |
Mechanism ntawm kev ua
Thaum peb noj, lub cev secretes incretin, uas yog tsim los ntawm pancreatic islet glucagon-zoo li peptide-1 (GLP-1) thiab gastric inhibitory peptide (GIP). Ob qho tshuaj hormones no tuaj yeem txhawb kev tso tawm ntawm insulin los ntawm pancreatic hlwb, yog li txo cov ntshav qab zib. Kuj tseem muaj ib qho enzyme hauv peb lub cev, hu ua dipeptidyl peptidase-4 (DPP-4), uas rhuav tshem cov secretin, thiab troxagliptin yog DPP-4 inhibitor. Nws yuav inhibit qhov degradation ntawm incretin los ntawm inhibiting DPP-4, yog li ntawd incretin yuav ua hauj lwm ntev, txhawb cov pancreatic hlwb kom secrete insulin, thiab tswj cov ntshav qab zib ntawm cov neeg mob ntshav qab zib ntawm tus nqi ib txwm.
Cim npe nrov: trelagliptin cas no.865759-25-7, Suav teb, manufacturers, lwm tus neeg, Hoobkas, kev cai, wholesale
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